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2021 NASCAR - Daytona 500 Winner Odds
<<-- 2020 Daytona 500 Winner 2022 Daytona 500 Winner -->>
Prior to the start of the race
Lines courtesy of William Hill
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| Driver | Odds | Result |
|---|---|---|
| Denny Hamlin | +850 | |
| Chase Elliott | +1000 | |
| Joey Logano | +1200 | |
| Kyle Larson | +1200 | |
| Ryan Blaney | +1200 | |
| William Byron | +1200 | |
| Aric Almirola | +1300 | |
| Kevin Harvick | +1300 | |
| Martin Truex Jr | +1300 | |
| Brad Keselowski | +1400 | |
| Kyle Busch | +1400 | |
| Bubba Wallace | +1500 | |
| Alex Bowman | +1600 | |
| Austin Dillon | +2000 | |
| Christopher Bell | +2200 | |
| Ricky Stenhouse Jr | +2500 | |
| Kurt Busch | +2800 | |
| Matt DiBenedetto | +3000 | |
| Ryan Newman | +3500 | |
| Ross Chastain | +4500 | |
| Jamie McMurray | +5000 | |
| Erik Jones | +6000 | |
| Tyler Reddick | +6000 | |
| Chris Buescher | +7000 | |
| Austin Cindric | +7500 | |
| Chase Briscoe | +7500 | |
| Cole Custer | +7500 | |
| Daniel Suarez | +7500 | |
| Michael McDowell | +10000 | ** WINNER ** |
| Corey Lajoie | +12500 | |
| David Ragan | +12500 | |
| Ryan Preece | +12500 | |
| Kaz Grala | +25000 | |
| Anthony Alfredo | +30000 | |
| BJ McLeod | +100000 | |
| Cody Ware | +100000 | |
| Joey Gase | +100000 | |
| Josh Bilicki | +100000 | |
| Quin Houff | +100000 | |
| Derrike Cope | +150000 |
